Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System

Surface microrollers have emerged as a promising microrobotic platform for navigation in the circulatory system future drug/gene delivery applications. The comprises various vessels with different dimensions, blood flow velocities, and regimes. Therefore, performance of surface would vary vessels. Herein, microrollers, diameters between 5 50 μm, inside systemic circulation including veins, venules, capillaries, arterioles, arteries is investigated computational fluid dynamics simulations. simulation environment consists simplified viscosity density blood, without red cells, cylindrical pipe. demonstrate successful upstream locomotion ability veins partially but fail to perform smaller due significant confinement effects. Overall, results presented here establish preliminary result vivo use microrollers.